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Leadership Team

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Matthew W. Semler, MD, MSc

Sep 2022

Chair of the Steering Committee: Matthew W. Semler, MD, MSc – Vanderbilt University Medical Center

Matthew W. Semler MD, MSc is an Assistant Professor of Medicine and Biomedical Informatics in the Division of Allergy, Pulmonary, and Critical Care Medicine at Vanderbilt University. Dr. Semler is a critical care physician and Associate Director of the Medical Intensive Care Unit at Vanderbilt University. Dr. Semler’s federally-funded research identifies non-patient-centered variation in current clinical practice, embeds pragmatic randomized trials into clinical care to understand which treatments produce the best outcomes for which patients, and implements the results into practice. Randomized trials he has helped lead, including six published in the New England Journal of Medicine or JAMA, have challenged longstanding dogma around common practices in fluid management, airway management, and respiratory support. Dr. Semler serves as Chair of the Steering Committee for the Pragmatic Critical Care Research Group, co-director of the Inpatient Division of the Learning Healthcare System at Vanderbilt University, and a member of the protocol committee for trials within the NHLBI PETAL Network.

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